If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death. It raises your risk of blood clots, heart attack, and stroke. This drug contains sulfonamide. You may have serious skin reactions. Report any skin rash to your doctor right away.
For pregnant women: This drug falls into one of two pregnancy categories, depending on how far along you are in your pregnancy. This category means two things:. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. For women who are breastfeeding: This drug has been shown to pass through breast milk. For seniors: This drug has been studied in a small number of people older than 65 years.
This dosage information is for celecoxib oral capsule. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:.
The typical dosage is mg taken once per day, or mg taken twice per day in evenly spaced doses. People with liver disease: Having liver disease may reduce your ability to clear this drug from your body, which could lead to more side effects. If you have moderate liver disease, your daily dose of celecoxib may be reduced by half. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Celecoxib oral capsule may be used for short-term or long-term treatment, depending on your condition. If you take too much: Taking too much increases your risk of experiencing side effects.
What to do if you miss a dose: If you miss your dose, take it as soon as you can. Never try to catch up by taking two doses at once. This could result in toxic side effects. How to tell if the drug is working: You may be able to tell this drug is working if you experience less pain. A prescription for this medication is not refillable.
You or your pharmacy will have to contact your doctor for a new prescription if you need this medication refilled. Your doctor will check your blood pressure before and during treatment with celecoxib. Your doctor may also do blood tests to check how well your liver and kidneys are functioning during treatment.
Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. There are other drugs available to treat your condition. Some may be more suitable for you than others.
Talk to your doctor about possible alternatives. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. If you have damage to tissues in your body, such as following an injury or surgery, or due to arthritis, your body makes prostaglandins.
These are hormones created by an enzyme called cyclooxygenase COX. Prostaglandins are made as part of the healing process, but they also cause inflammation and pain. Prostaglandins are also responsible for causing your uterus to contract during your menstrual period.
The contractions cause the lining of the uterus to be expelled, and they also cause menstrual cramps. Celebrex works by stopping COX from making prostaglandins. This reduces inflammation and relieves pain. Celebrex starts to work soon after you start taking it. The drug can typically relieve acute pain like menstrual cramps or pain following surgery within 60 minutes of you taking a dose.
The anti-inflammatory effect of Celebrex takes a little longer. If you have arthritis, you may need to take Celebrex for a few days before the full effect is reached. However, in clinical studies , Celebrex was found to significantly reduce osteoarthritis pain within 24 to 48 hours of starting treatment. Certain pain -relieving drugs have a high potential for misuse.
This can sometimes lead to addiction or dependence on these drugs and withdrawal symptoms when you stop taking them. Drugs that are associated with these problems are primarily opioid pain relievers, such as codeine, oxycodone OxyContin , and hydrocodone Percocet. Opioids are sometimes known as narcotics. Due to their potential for misuse and dependence, these drugs are controlled substances.
These laws help ensure that these drugs are used safely. If you have concerns about withdrawal or dependence for any medications you take, including Celebrex, talk with your doctor.
You may wonder how Celebrex compares with other medications that are prescribed for similar uses. Here we look at how Celebrex and ibuprofen are alike and different. Celebrex is a brand-name drug that contains celecoxib. Ibuprofen is a generic drug. Ibuprofen is also available under several brand names, including Ibu-Tab, Advil, and Motrin. The drug is available only by prescription.
Ibuprofen comes as a tablet, capsule, and liquid suspension that you swallow. These forms of the drug can be taken up to four times a day. Ibuprofen also comes as an infusion. They can give this form of ibuprofen up to four times a day. Ibuprofen is available OTC and by prescription. OTC brands of ibuprofen include Advil and Motrin. Higher doses of ibuprofen are available only by prescription under brand names such as Ibu-Tab.
Therefore, these medications can cause very similar side effects, but some different ones as well. Below are examples of these side effects. These lists contain up to 10 of the most common mild side effects that can occur with Celebrex, with ibuprofen, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Celebrex, with ibuprofen, or with both drugs when taken individually.
NSAIDs like Celebrex and ibuprofen are well accepted as effective pain relievers for these conditions. And prescribed doses of ibuprofen are considered to be as similarly effective as Celebrex. Lower doses of ibuprofen that you can buy OTC may not be as effective as Celebrex.
Both drugs are widely prescribed to treat the conditions listed above. For example, NSAIDs such as Celebrex and ibuprofen are recommended in guidelines for treating pain following musculoskeletal injury , back pain , and menstrual cramps.
However, there can be differences in the risk of side effects with these drugs. For example, lower doses of ibuprofen that you can buy OTC are less likely than Celebrex to cause serious side effects. On the other hand, a large clinical study found that Celebrex is less likely than higher prescribed doses of ibuprofen to cause these serious side effects.
According to estimates on GoodRx. Celebrex is a brand-name drug. Brand-name medications usually cost more than generics. Like ibuprofen above , the drug Mobic has uses similar to those of Celebrex. Celebrex contains celecoxib. Mobic contains meloxicam. Mobic is approved to treat JRA in children who weigh about pounds 60 kilograms or more. Therefore, these medications can cause very similar side effects. This list contains up to 10 of the most common mild side effects that can occur with both Celebrex and Mobic when taken individually :.
This list contains examples of serious side effects that can occur with both Celebrex and Mobic when taken individually :. The drugs are considered to be similarly effective and are both widely prescribed.
For example, Celebrex is less likely than Mobic to cause ulcers or bleeding in your stomach or intestines. Celebrex and Mobic are both brand-name drugs. The generic form of Celebrex is celecoxib. And the generic form of Mobic is meloxicam. As with all medications, the cost of Celebrex can vary. To find current prices for Celebrex capsules in your area, check out GoodRx. The cost you find on GoodRx. Before approving coverage for Celebrex, your insurance company may require you to get prior authorization.
This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered. If you need financial support to pay for Celebrex, help is available. Pfizer Inc. Celebrex is available in a generic form called celecoxib. And generics tend to cost less than brand-name drugs. To find out how the cost of celecoxib compares to the cost of Celebrex, visit GoodRx.
They may have a preference for one version or the other. You may take Celebrex with certain other medications to help control your pain. For example, Celebrex is often used with acetaminophen Tylenol.
This is a different type of pain-relieving drug that you buy without a prescription. DMARDs help stop your immune system from attacking your joints.
If your dose of Celebrex is up to milligrams mg twice a day, you can take it either with or without food. But if your doctor has recommended taking a higher dose of mg twice a day, you should take this with food. But if you have trouble swallowing the drug, you can split open the capsules and sprinkle the contents onto a spoonful of applesauce. The applesauce should be room temperature or cool.
The possible risks of taking Celebrex during pregnancy depend on how far along you are in the pregnancy. Animal studies found harmful effects from Celebrex to fetuses. Using nonsteroidal anti-inflammatory drugs NSAIDs at or after 20 weeks of pregnancy may increase the risk of certain problems. Your doctor may recommend that you avoid Celebrex at 30 weeks of pregnancy and after. Studies have shown that NSAIDs can have harmful effects on a fetus if taken during the last trimester of pregnancy.
They can help you weigh the possible risks and benefits of taking this drug during pregnancy. In women, taking Celebrex can reduce your fertility for a time by delaying ovulation. This effect goes away when you stop taking Celebrex. The possible risks of taking Celebrex while pregnant depend on how far along you are in your pregnancy.
Celebrex may pass into your breast milk. This drug has boxed warnings. It alerts doctors and patients about drug effects that may be dangerous. These problems include slow healing sores called ulcers , bleeding, and perforations holes in your digestive tract. In some cases, these digestive problems can be fatal. Before taking Celebrex, talk with your doctor about your health history. Celebrex may not be right for you if you have certain medical conditions or other factors affecting your health.
These include:. Using more than the recommended dosage of Celebrex can lead to serious side effects. Do not use more Celebrex than your doctor recommends. You can also call the American Association of Poison Control Centers at or use their online tool. But if your symptoms are severe, call or your local emergency number, or go to the nearest emergency room right away. When you get Celebrex from the pharmacy, the pharmacist will add an expiration date to the label on the bottle.
This date is typically 1 year from the date they dispensed the medication. The expiration date helps guarantee that the medication is effective during this time. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.
How long a medication remains good can depend on many factors, including how and where you store the medication. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment. This article provides several useful tips on medication disposal.
You can also ask your pharmacist for information on how to dispose of your medication. Celebrex is also FDA-approved to treat juvenile rheumatoid arthritis in children ages 2 years and older. NSAIDs act by stopping the production of prostaglandins. These contractions cause primary dysmenorrhea. Celebrex mainly inhibits the action of COX By stopping the production of prostaglandins, Celebrex reduces pain and inflammation.
After oral administration, the maximum plasma concentration Cmax of celecoxib is reached after approximately 3 hours. Steady state is reached after approximately 5 days of multiple dosing. These people should start treatment at the lowest dose if they weigh less than 50 kg. Celecoxib is mainly metabolized in the liver by CYP2C9 to inactive metabolites.
Celecoxib has an effective half-life of approximately 11 hours. Celebrex has not been studied in people with severe renal or hepatic impairment and is not recommended in these people. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date.
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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